Onset-To-Door and Cognitive Function in Ischemic Stroke patients

Abstract

Stroke could cause a decrease in cognitive function. Early diagnosis and prompt treatment play an important role in preventing the advancement of the disease. This study was aimed to determine the correlation between onset-to-door and cognitive function in ischemic stroke patients. This research was conducted in 31 ischemic stroke patients. Data collected from medical records and cognitive function examinations were measured using the Mini-Mental State Examination (MMSE). Onset-to-door (OTD) was the period from the first onset of symptoms of ischemic stroke to getting help in the emergency room Dr Ramelan naval hospital, which was divided into two groups: the golden period and non-golden period. Data were analyzed using Somer’s d correlation and Mann-Whitney U test. The results of majority (67.7%) of ischemic stroke patients had OTDin the golden period and 45.2% hadno cognitive impairment. Correlation test between OTD and cognitive function showed d = 0.576, p = 0.001. Orientation and language function were found to be different between golden period and non-golden period groups (p = 0.020 and p = 0.001, respectively). It was concluded that onset-to-door is associated with impaired cognitive function in ischemic stroke patients, especially in orientation and language function.