Onset of Afebrile Seizure in Transient Erythroblastopenia of Childhood

Toru Watanabe,Maho Nagasawa,Ryoichi Kitagata,Tomoka Matsuda,Teruaki Hongo,Masami Shirai,Akira Endoh,Kenichi Kinjyo,Keiko Hirano

doi:10.15344/2455-2364/2015/102

Abstract

We describe a girl aged 2 years 2 months who presented with anemia and transient erythroblastopenia of childhood with the onset of afebrile seizure. She recovered spontaneously from transient erythroblastopenia of childhood 1 month after diagnosis without the need of any packed red cell transfusions.

Highlights

Transient erythroblastopenia of childhood (TEC) is a self-limited anemia and a disorder of young children (i.e., 3 months to 4 years) characterized by anemia associated with reticulocytopenia
2 years and 2 months old, with TEC associated with the onset of afebrile seizure
The onset age of Diamond-Blackfan anemia (DBA) is different from that of TEC and DBA has to be included in the differential diagnosis of TEC, the onset of TEC may be difficult to distinguish from DBA

Summary

Introduction

Transient erythroblastopenia of childhood (TEC) is a self-limited anemia and a disorder of young children (i.e., 3 months to 4 years) characterized by anemia associated with reticulocytopenia. 2 years and 2 months old, with TEC associated with the onset of afebrile seizure. Afebrile seizure as a complication of TEC is rare and we report this case along with references to previous studies. She had low serum IgG (572 mg/dL) and high erythropoietin (EPO) (563 mIU/mL) levels (Figure1).

Results

Conclusion