Online Detection of High-solid and Multi-phase Bioprocess Parameters

Abstract

Parameter monitoring is the key in high-solid and multi-phase bioprocess, which is also a core problem to be solved in its industrialization process. While solid-state substrate has the characteristics of heterogeneity, poor mobility, low moisture content, and parameters (temperature, moisture content, biomass) with large gradient, resulting in great difficulties for parameters monitoring and control in reaction process and proposing higher requirements for parameters monitoring and control. This chapter focuses on parameters monitoring and control in solid-state fermentation (SSF) and high-solid enzymatic hydrolysis of biomass, in order to obtain more important parameters, which could provide the guidance for optimizing and regulation of the high-solid and multi-phase bioprocess.