Abstract
Diazoketones and diazoesters react with tertiary amines in the presence of copper powder to form transient ammonium ylides. These ylides undergo facile [1,2]-shift from N to C (Stevens rearrangement) of the best migrating group. Overall, α-substituted α-amino ketones or α-amino esters are formed in one step from simple reactants
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have