One-year outcomes of off- and on-pump coronary artery bypass grafting: PROMOTE patency trial.

Abstract

Earlier we reported 3-month graft patency and clinical outcomes of prospective randomized comparison of off-pump and on-pump multivessel coronary artery bypass surgery to evaluate outcomes and graft patency (PROMOTE patency) trial. We now report major adverse cardiac and cerebrovascular events (MACCE) at 1year of patients who underwent coronary artery bypass grafting (CABG) using either off-pump technique or on-pump technique. The PROMOTE patency trial is a two-arm, prospective, randomized, multicentre trial, and enrolled 320 patients with multivessel coronary artery disease from March 2016 through March 2017 at 6 centres and were randomly assigned to undergo either off-pump CABG (OPCAB) (n = 158 patients) or on-pump CABG (n = 162 patients). The outcomes at 1year were assessed. One mortality (0.64%) occurred in off-pump group (at 30days) and 4 (2.48%) in on-pump group (1 at 30days, 2 at 3months, and 1 at 1year) (p = 0.37). There was no difference between off-pump and on-pump groups in the outcomes of nonfatal myocardial infarction (1 in off-pump and 2 in on-pump group, p = 1.00) and cerebrovascular accident (none in off-pump and 2 in on-pump group, p = 0.49). Repeat revascularization was done in one patient in each group (p = 1.00). There was no significant difference in the incidence of MACCE between off-pump and on-pump CABG group at 1year.