Abstract

In the paper we discuss a biomechanical model of microcirculation and transcapillary metabolism and present a mathematical model of metabolic processes occurring in microcirculation level. We conside the following interrelated processes: the flow of blood (a non-Newtonian fluid) in capillaries; filtration and reabsorption of fluid through the wall of the arterial capillary into the surrounding tissue and from this one back to the venous capillary; the movement of fluid in the interstices, the exchange of substances between the interstitial fluid and tissue cells, drainage into the lymphatic capillaries. Biological tissue is modeled as a porous, resilient, isotropic matrix or frame saturated with a fluid of the same type. It is believed that the liquid is contained in the pores of the matrix. The study of microcirculation allows you to better understand the complex interlinked processes of metabolism in the body, identify the causes of pathologies and suggest possible treatment interstitium.

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