Abstract
Abstract Biodegradable chitosan-based nanospheres were prepared by the one-step polymerization of l-phenylalanine-N-carboxylic anhydride initiated by water-soluble chitosan. The obtained chitosan-g-poly(phenylalanine) nanospheres with a diameter of 220–290 nm showed a strong positive charge, and thus it will be valuable as novel biodegradable cationic nanosphere.
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