Abstract
One single drug combination of bromelain and Boswellia serrata casperome®: effects on postoperative Edema in open incisional abdominal hernia repair. Prospective randomized clinical trial
Highlights
Aim of this study is to investigate the significant postoperative benefits on patients about edema of tissues after incisional hernia repair with synthetic mesh using a combination of Bromelain (200 mg) and Boswellia Serrata Casperome® (200 mg), evaluated by ultrasound (US), and compared to control patients group
The edema was already reduced in the treated group compared to the control group at 15 post-surgery days; this reduction became statistically significant starting from US result at 30 post-surgery days of drug treatment (p=0.043) and was even greater in the US result after 60 post-surgery days (p=0.001). Results obtained in this preliminary study showed a rapid and significant improvement in postoperative edema outcome of incisional hernia repair in patients treated with drug
We investigated if a novel dietary supplement based on a combination of Bromelain (200 mg) and Boswellia Serrata Casperome® (200 mg), can demonstrate a suitable reduction of postoperative inflammation and seroma formation in patients subjected to abdominal incisional hernia repair, in order to avoid synthesis of pro-inflammatory agents, such as leukotriene-4, 5-lipoxygenase, 5-hydroperoxydeicotetraenoic acid, prostaglandins and kinins
Summary
Aim of this study is to investigate the significant postoperative benefits on patients about edema of tissues after incisional hernia repair with synthetic mesh using a combination of Bromelain (200 mg) and Boswellia Serrata Casperome® (200 mg), evaluated by ultrasound (US), and compared to control patients group (not treated with drugs). General consensus in literature is represented by tension-free hernia repair with use of mesh, observing a significantly reduction of recurrence rates. Even today, perfect mesh for incisional hernia repair doesn’t exist like as doesn’t exist a standardization technique for repairing this kind of wall post-operative defect. Incisional hernia repair with mesh reduces recurrence rates but doesn’t exist a technique standardization. One of major complicance of this kind of repair is seroma formation or tissues’ edema near the mesh. For this reason, it is important to reduce edema and inflammation incidence [2]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
