One‐pot, Three‐component Synthesis of a Series of New Bis‐pyrrolo[2,3‐d]pyrimidines in the Presence of TPAB under Reflux Conditions

Abstract

A one‐pot, three‐component reaction of 1,4‐phenylene‐bis‐glyoxal, 6‐aminouracils, and dimedone or barbituric acid derivatives in the presence of tetrapropylammonium bromide (5 mol%) in ethanol under reflux conditions gave a series of new bis‐pyrrolo[2,3‐d]pyrimidine derivatives in high yields.