Abstract
AbstractAn efficient Bi(OTf)3‐catalyzed transformation of unprotected propargylic alcohols has been developed, affording a general, one‐pot approach to access diverse pyrazoles via sequential iodo‐intercepted Meyer‐Schuster rearrangement, cyclocondensation of NH2NH2 ⋅ H2O and α‐iodo enones/enals generated in situ, and iodine elimination. This transformation tolerates a wide range of substrates and is reliable on a large scale. The high yields and convenient experimental operations make it a valuable method for the construction of pyrazole derivatives.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
