One-Pot Synthesis of SiO2@Ag Mesoporous Nanoparticle Coating for Inhibition of Escherichia coli Bacteria on Various Surfaces.

Sukhbayar Gankhuyag,Kyoung Lee,Dong Sik Bae,Seunghyun Lee

doi:10.3390/nano11020549

Sukhbayar Gankhuyag, Kyoung Lee + Show 2 more

Open Access

https://doi.org/10.3390/nano11020549

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Abstract

Silver nanoparticles (Ag NPs) as antibacterial agents are of considerable interest owing to their simplicity, high surface area to volume ratio, and efficient oligodynamic properties. Hence, we investigated the synthesis of silica-supported Ag NPs (SiO2@Ag) as an effective antibacterial agent by using a wet-impregnation method. The formation of SiO2@Ag with Ag NP (5–15 nm diameter) on the silica particle (100–130 nm diameter) was confirmed with transmission electron microscopy (TEM). The study on antibacterial activity was performed in a liquid culture to determine the minimum inhibitory concentration (MIC) against Escherichia coli (E. coli) and Bacillus subtilis (B. subtilis) bacteria. Both bacteria are chosen to understand difference in the effect of Ag NPs against Gram-negative (E. coli) and Gram-positive (B. subtilis) bacteria. SiO2@Ag mesoporous nanoparticles had excellent antibacterial activity against E. coli bacteria and fully restricted the bacterial growth when the material concentration was increased up to 1.00 mg/mL. In addition, the obtained material had good adhesion to both steel and polyethylene substrates and exhibited a high inhibition effect against E. coli bacteria.

Highlights

Silver nanoparticles (Ag NPs) have received considerable attention owing to their potential for applications such as catalysis, sensing, food packaging, water disinfection, drug delivery, and antimicrobial coatings [1,2,3,4,5,6,7,8,9]
The biofouling of surfaces in biomedical equipment, wastewater treatment system, and water shipment are adverse effects that result in the growth and aggregation of microbes caused by microorganisms that lead to the extracellular polymer substances (EPS) on the surface [10]
We investigated a one-pot synthesis route for SiO @Ag mesoporous

Summary

Introduction

Silver nanoparticles (Ag NPs) have received considerable attention owing to their potential for applications such as catalysis, sensing, food packaging, water disinfection, drug delivery, and antimicrobial coatings [1,2,3,4,5,6,7,8,9]. The biofouling of surfaces in biomedical equipment, wastewater treatment system, and water shipment are adverse effects that result in the growth and aggregation of microbes caused by microorganisms that lead to the extracellular polymer substances (EPS) on the surface [10]. Such an event results in an inefficient system and may cause an outbreak of pathogenic diseases. An excessive intake of Ag NPs is known to be harmful to the mammalian organ system [13]

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