One‐pot synthesis of pyrido[2,3‐d:5,6‐d′]dipyrimidines using CoFe2O4@SiO2‐PA‐CC‐guanidine‐SA magnetic nanoparticles in water

Abstract

In this study, the synthesis of pyrido[2,3‐d:5,6‐d′]dipyrimidines using CoFe2O4@SiO2‐PA‐CC‐guanidine‐SA magnetic nanoparticles with excellent yields has been reported. Pyrido[2,3‐d:5,6‐d′]dipyrimidines were synthesized from the four‐component reaction of barbituric acid derivatives, benzaldehyde derivatives and ammonium acetate in water at room temperature. The synthesized catalyst was identified using Fourier‐transform infrared spectroscopy (FT‐IR), scanning electron microscopy (SEM), energy‐dispersive X‐ray spectroscopy (EDX), X‐ray powder diffraction (XRD), thermogravimetric analysis (TGA) and vibrating sample magnetometer (VSM) techniques.