Abstract
A series of potentially bioactive compounds having either indole or indene frameworks such as dihydroindenone and indolinone derivatives were synthesized in good to high yields by one-pot, multi-component reaction of various amines, trichloroacetonitrile, ninhydrin or isatin, and 2-hydroxy-1,4-naphthoquinone. The present method offers desirable advantages including mild conditions, absence of catalyst, simple workup procedure, and easy purification process with no chromatographic technique.
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