One Pot Synthesis of β-Amino Ketone Derivatives Catalyzed by Polystyrene-supported Ferric Chloride

Abstract

A novel polystyrene-supported ferric chloride catalyst was prepared and characterized by IR,XRD and SEM. The catalyst exhibited excellent catalytic activities for the synthesis of β-amino ketone derivatives via one-pot Mannich reaction from acetophenone,aromatic aldehydes and aromatic amines. The catalyst could be recycled easily and the activity of the catalyst maintained after 4 cycles.