Abstract
The preparation of N-(α-ferrocenylalkyl) amino acid esters under neutral conditions by the reaction of in situ generated (α-ferrocenylalkyl)carbonates with amino acid esters is described. The method allows regioselective one-pot alkylation of a series of amino acid esters at the amino group, as well as diastereoselective preparation of ferrocenylalkyl substituted amino acid esters from (S)-(+)-α-ferrocenylethanol.
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