Abstract
A new one-pot and efficient four-component condensation of benzaldehyde derivatives, enolizable ketones, acetyl chloride and acetonitrile or benzonitrile in the presence of ferric hydrogensulfate as an inexpensive and effective catalyst for the synthesis of β-amido ketones and esters is described. The present methodology offers several advantages, such as good yields, short reaction times and a recyclable catalyst with a very easy work up.
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