Abstract
A one-pot efficient synthesis of β-aryl-β-sulfanyl ketones is introduced via a tandem aldol condensation-thia-Michael addition process using NaOH in the poly ethylene glycol (PEG-200). Addition of different thiols in situ generated from the reaction of alkyl halides with thiourea to chalcones, formed in situ from the condensation of acetophenone derivatives with benzaldehydes, led to a high yielding synthesis of the products.
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