Abstract

The Randomized Play-the-Winner (RPW) and the Generalized Friedman's Urn (GFU)model are very useful in clinical trials. In this paper, a new adaptive design is proposed which is beneficial for selecting the better of two competing treatments in future. It is more reasonable that the new design of two arms considers α and β belong to GFU model as parameters rather than constants. The new design has some desirable asymptotic properties.

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