One New Ten-membered Lactone from Phomopsis sp. B27, an Endophytic Fungus of Annona squamosa.

Abstract

To study the chemical constituents of Phomopsis sp. B27, an endophytic fungal strain of Annona squamosa L. The extract was isolated and purified by column chromatography. The structures of chemical components were determined by spectroscopic analyses including 1D-, 2D-NMR and MS data. Five compounds were isolated and determined as a ten-membered lactone, namely phomolide C (1), 1-methoxy-8-hydroxy-9,10-anthraquinone (2), 1,8-dihydroxy-9,10-anthra-quinone (1,8-DHA) (3), cytosporone C (4) and altiloxin A (5). Compound 1 is a new ten-membered lactone; and compounds 1-5 were isolated from the genus Phomopsis for the first time.