One-lung flooding reduces the ipsilateral diaphragm motion during mechanical ventilation

Thomas Günther Lesser,Harald Schubert,Daniel Güllmar,Jürgen R Reichenbach,Frank Wolfram

doi:10.1186/s40001-016-0205-1

Abstract

BackgroundDiaphragm motion during spontaneous or mechanical respiration hinders image-guided percutaneous interventions of tumours in lung and upper abdomen. Motion-tracking methods can be applied but increase procedure complexity and procedure time. One-lung flooding (OLF) generates a suitable acoustic pathway to lung tumours and likely suppress diaphragm motion. The aim of this study was to quantify the effect of OLF on ipsilateral diaphragm motion during contralateral one-lung ventilation.MethodsTo measure the diaphragm motion, M-mode ultrasonography of the right hemidiaphragm was performed during spontaneous breathing and mechanical ventilation, as well as after right-side lung flooding, in three pigs. Diaphragm motion was analysed using magnetic resonance images during left-side lung flooding and mechanical ventilation, in four pigs.ResultsDouble-lung ventilation increased the diaphragm movement in comparison with spontaneous breathing (17.8 ± 4.4 vs. 12.2 ± 3.4 mm, p = 0.014). Diaphragm movement on the flooded side during contralateral one-lung ventilation was significantly reduced compared to that during double-lung ventilation (3.9 ± 1.0 vs. 17.8 ± 4.4 mm, p = 0.041). By analysing the magnetic resonance images, the hemidiaphragm on the flooded side showed an average displacement of 4.2 mm, a maximum displacement of 15 mm close to the ventilated lung and no displacement at the lateral side.ConclusionOLF leads to a drastic reduction of diaphragm motion on the ipsilateral side which implies that targeting and motion compensation algorithms for interventions like high-intensity focused ultrasound ablation of intrapulmonary and hepatic lesions might not be required.

Highlights

Diaphragm motion during spontaneous or mechanical respiration hinders image-guided percutaneous interventions of tumours in lung and upper abdomen
It can be assumed that the diaphragmatic motion on the flooded side should be reduced, which will be beneficial for interventions that require One-lung flooding (OLF) for an acoustic access to lung or upper abdomen
The aim of this study was to quantify the effect of OLF on ipsilateral diaphragm motion during contralateral one-lung ventilation using an in vivo large animal model

Summary

Introduction

Diaphragm motion during spontaneous or mechanical respiration hinders image-guided percutaneous interventions of tumours in lung and upper abdomen. Organ motion requires gating of imaging techniques and hinders the precise targeting of interventions in lung and upper abdomen [1, 2]. Beside all of the available target tracking methods, a reduction of diaphragm motion and thereby avoidance of target motion is preferred Special ventilation techniques, such as one-lung ventilation, high-frequency jet ventilation (HFJV) and high-frequency oscillatory ventilation (HFOV) can reduce movement of the diaphragm and avoid gating or motion compensation for MR imaging [9, 10]. It can be assumed that the diaphragmatic motion on the flooded side should be reduced, which will be beneficial for interventions that require OLF for an acoustic access to lung or upper abdomen

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