Abstract
Tumor cells in blood are difficult to find, but if tools were available to reliably detect and isolate them, physicians would have the wherewithal to better discover, study, and treat early-stage cancers. The start-up company RareCyte is racing against academicians and one large firm to develop such tools. Launched in 2009 by electrical engineer and serial entrepreneur Ronald C. Seubert, RareCyte has developed a fluorescent imaging system that can detect one lethal cancer cell hiding among 50 billion normal blood cells. The Seattle-based firm is now engaged in clinical studies with partners at the University of Washington, Seattle; the Seattle Cancer Care Alliance; and the Fred Hutchinson Cancer Research Center. To date, RareCyte has raised $11 million from family, friends, and a private equity investor to develop its equipment, software, and reagent kits. Seubert says the firm will start seeking regulatory approvals in late 2013, which would open the way ...
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