Abstract

Chorionic carcinoma is a highly malignant gynecological tumor, frequently originating from trophoblastic cells in the uterus after fertilization. Early erosion releases cancerous cells into the circulation to invade surrounding organs without primary symptoms and signs. One case of choriocarcinoma sellar region metastasis was analyzed, utilizing clinical data, MRI and pathological examinations, and clinical characteristics were summarized. Choriocarcinoma sellar region metastasis is easily misdiagnosed. We examined the literature and original resources to summarize the clinical characteristics of choriocarcinoma sellar region metastasis and discuss available therapies. This case study of a metastasis of choriocarcinoma to the sellar region provides important new data on the incidence and pathology of this rare disease.

Highlights

  • Chorionic carcinoma is a highly malignant gynecological tumor, frequently originating from trophoblastic cells in the uterus after fertilization

  • Primary chorionic carcinoma is associated with lung metastasis in about one-third of cases [2], and the incidence of brain metastasis is 6.3–22.5 % [3]

  • We examined the literature and original resources to summarize the clinical characteristics of choriocarcinoma sellar region metastasis and discuss available therapies

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Summary

Introduction

Chorionic carcinoma is a highly malignant gynecological tumor, frequently originating from trophoblastic cells in the uterus after fertilization. Methods: One case of choriocarcinoma sellar region metastasis was analyzed, utilizing clinical data, MRI and pathological examinations, and clinical characteristics were summarized. We examined the literature and original resources to summarize the clinical characteristics of choriocarcinoma sellar region metastasis and discuss available therapies. Conclusion: This case study of a metastasis of choriocarcinoma to the sellar region provides important new data on the incidence and pathology of this rare disease. Primary chorionic carcinoma is associated with lung metastasis in about one-third of cases [2], and the incidence of brain metastasis is 6.3–22.5 % [3]. We report one case of chorionic carcinoma brain metastasis to the sellar area and summarize the recent literature

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