Abstract

Ultrasonic acoustic levitation has been recently applied successfully for protein crystallography experiments. One of the development goals of such an acoustic levitation diffractometer is to realize a fully automated high-throughput crystallography pipeline at room temperature that integrates an on-demand sample delivery mechanism from crystallization plates. To study the feasibility of the on-demand droplet ejection from crystallization plates, we prepared acoustic ejectors and tested their characteristics. Acoustic droplet ejection from a vertically positioned crystallization plate and coalescence of the ejected droplet with the levitated droplet in an acoustic levitator was successfully demonstrated, indicating that feasibility of the proposed instrument.

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