Abstract
Oncometabolite Fingerprinting In article number 2101591, Dean Amir, Gili Bisker, and co-workers use DNA-functionalized single-walled carbon nanotubes (SWCNTs) for the recognition and quantification of the oncometabolite D-2-hydroxyglutarate (D2HG). The DNA-SWCNT sensors can distinguish D2HG from closely-related metabolites, including the enantiomer L-2-hydroxyglutarate, owing to measurable modulations of the near-infrared fluorescence of the SWCNT. These nanosensors open new opportunities for the advancement of cancer research.
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