Oncological and functional outcome after surgical treatment of early glottic carcinoma without anterior commissure involvement.

Jovica Milovanovic,Ana Jotic,Bojan Banko,Aleksandar Trivic,Vojko Djukic,Aleksandar Milovanovic,Sanja Krejovic-Trivic,Vera Artiko,Bojan Pavlovic,Andjela Milovanovic

doi:10.1155/2014/464781

Abstract

Introduction. Glottic carcinoma can be successfully diagnosed in its early stages and treated with high percentage of success. Organ preservation and optimal functional outcomes could be achieved with wide array of surgical techniques for early glottic cancer, including endoscopic approaches or open laryngeal preserving procedures, making surgery the preferred method of treatment of early glottic carcinoma in the last few years. Material and Methods. Prospective study was done on 59 patients treated for Tis and T1a glottic carcinoma over a one-year time period in a tertiary medical center. Patients were treated with endoscopic laser cordectomy (types II–IV cordectomies according to European Laryngological Society classification of endoscopic cordectomies) and open cordectomy through laryngofissure. Follow-up period was 60 months. Clinical and oncological results were followed postoperatively. Voice quality after the treatment was assessed using multidimensional voice analysis 12 months after the treatment. Results. There were no significant differences between oncological and functional results among two groups of patients, though complications were more frequent in patients treated with open cordectomy. Conclusion. Endoscopic laser surgery should be the first treatment of choice in treatment of early glottic carcinomas, though open approach through laryngofissure should be available for selected cases where anatomical factors present limiting adequate tumor removal.

Highlights

Glottic carcinoma can be successfully diagnosed in its early stages and treated with high percentage of success
Treatment options include open cordectomy through laryngofissure, endoscopic cordectomy, or radiotherapy, but treatment guidelines are still based on low-level evidence
Organ preservation and optimal functional outcomes could be BioMed Research International achieved with wide array of surgical techniques, including endoscopic approaches or open laryngeal preserving procedures, making surgery good alternative and more preferred treatment choice to radiotherapy [5,6,7]

Summary

Introduction

Glottic carcinoma can be successfully diagnosed in its early stages and treated with high percentage of success. Organ preservation and optimal functional outcomes could be achieved with wide array of surgical techniques for early glottic cancer, including endoscopic approaches or open laryngeal preserving procedures, making surgery the preferred method of treatment of early glottic carcinoma in the last few years. In many European countries, radiotherapy was the first choice of treatment for patients with early glottic cancer, with its high local control rates and satisfactory functional results [2, 3]. Organ preservation and optimal functional outcomes could be BioMed Research International achieved with wide array of surgical techniques, including endoscopic approaches or open laryngeal preserving procedures, making surgery good alternative and more preferred treatment choice to radiotherapy [5,6,7]

Objectives

Methods

Results

Conclusion