Abstract
Background: The impact of breast appearance after breast cancer surgical treatment on patients’ quality of life led to the development of the oncoplastic approach. However, studies reporting oncologic results associated with this treatment strategy are scarce. This cross-sectional study was designed to assess oncologic outcomes among patients who underwent oncoplastic surgery. Methods: A total of 190 breast cancer patients who underwent breast-conserving surgery were enrolled. Fifty of them underwent oncoplastic surgery and 140 had none breast reconstruction procedure (control group). All surgeries were performed by the same surgical team. Results: Groups were similar with regard to staging, histological type, grade of the tumor, presence of intraductal component, hormone receptors and nodal commitment. Patients in oncoplastic surgery group had larger tumors (ρ = 0.001) and more lymphovascular invasion (ρ = 0.047). Further, a higher proportion of them underwent chemotherapy (ρ = 0.030). Follow-up time of control group was longer (ρ = 0.05), and these patients also had a longer relapse-free survival time (ρ = 0.001). Local recurrence rate was 5.8% (11/190) and it was significantly greater in the oncoplastic surgery group (8/11, ρ = 0.001). Time to local recurrence after surgery was longer in oncoplastic surgery group (ρ = 0.002). Overall, patients in oncoplastic surgery group were younger (ρ = 0.001), but at the time of local recurrence, patients in oncoplastic surgery group were older than those in control group (ρ = 0.0002). Conclusions: Among the studied patients, local recurrence rate was greater in those who underwent oncoplastic surgery.
Highlights
Conservative surgery has become the standard surgical approach to early breast cancer since the studies of Veronesi et al and Fisher et al [1,2,3]
Local recurrence rate was 5.8% (11/190) and it was significantly greater in the oncoplastic surgery group (8/11, ρ = 0.001)
In the past two decades, it has been observed that conservative surgery has produced poor cosmetic results in many cases, contradicting the present goal of breast cancer treatment, namely a better local control of the disease with presservation of the breast contours [5,8,9]
Summary
Conservative surgery has become the standard surgical approach to early breast cancer since the studies of Veronesi et al and Fisher et al [1,2,3]. Changes include the conservative surgical approach to large tumors [5], the fact that resection of the skin and aponeurosis is no longer routinely performed, introduction of neoadjuvant chemotherapy, and immediate breast reconstruction, which has become part of the procedure. In the past two decades, it has been observed that conservative surgery has produced poor cosmetic results in many cases, contradicting the present goal of breast cancer treatment, namely a better local control of the disease with presservation of the breast contours [5,8,9]. Studies reporting oncologic results associated with this treatment strategy are scarce This cross-sectional study was designed to assess oncologic outcomes among patients who underwent oncoplastic surgery. Conclusions: Among the studied patients, local recurrence rate was greater in those who underwent oncoplastic surgery
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
