Abstract
Background: Oral squamous cell carcinoma [OSCC] is the most common malignancy of the oral cavity. The etiological agents for OSCC are tobacco, betel quid, smoking, and alcohol. Oral cancer also has a genetic basis that is mediated by oncogenes. 
 Aim: The aim of the survey was to evaluate the knowledge about the role of oncogenes in oral oncogenesis among undergraduate dental students. 
 Materials and Methods: The study was a questionnaire-based survey and the respondents were to fourth year or interns of an undergraduate dental school. The sample size of the study was 100 and simple random sampling was used for choosing the sample population. The collected data was validated, tabulated, and analyzed with Statistical Package for Social Sciences for Windows, version 20.0 (SPSS Inc., Chicago, IL, USA), and results were obtained.
 Results and Conclusion: 25% of the respondents were fourth-year students and 75% were interns. About 98% of respondents were aware of the genetic basis of oral cancer. However, their knowledge about the role of oncogenes in oral cancer was very limited. A statistically significant association [P<0.05] was seen between the year of study and knowledge about oncogenes. Hence, measures have to be taken to impart knowledge about oncogenes for better diagnosis and targeted therapy.
Highlights
A neoplasm can be defined as an abnormal mass of tissue the growth of which is uncoordinated with that of normal tissues and proceeds in the same excessive manner even after the cessation of stimulus that evoked the change
A strong genetic basis exists for the pathogenesis of Oral Squamous Cell Carcinoma
Mutation of proto-oncogene results in an oncogene that propagates the process of oncogenesis
Summary
A neoplasm can be defined as an abnormal mass of tissue the growth of which is uncoordinated with that of normal tissues and proceeds in the same excessive manner even after the cessation of stimulus that evoked the change. Neoplasm can be of different origins and can involve the epithelial or mesenchymal components. It can be benign or malignant in nature. Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity. Oral squamous cell carcinoma [OSCC] is the most common malignancy of the oral cavity. Aim: The aim of the survey was to evaluate the knowledge about the role of oncogenes in oral oncogenesis among undergraduate dental students. Materials and Methods: The study was a questionnaire-based survey and the respondents were to fourth year or interns of an undergraduate dental school. Results and Conclusion: 25% of the respondents were fourth-year students and 75% were interns. About 98% of respondents were aware of the genetic basis of oral cancer.
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