Abstract

We present a cell manipulation method by using vibration induced whirling flow. The local flow is induced just around a micropillar by applying circular vibration to the micropillar. By patterning a micropillar array on a chip and applying circular vibration to the chip, flow for cell transport can be generated along the array. As an application, we demonstrate a single cell extraction using the vibration-induced flow and single cell catcher made by thermo-responsive gel. Target cells are transported to the single cell catcher by vibration induced flow and caught by the single cell catcher. We tried 30 times single cell extraction, succeeded in 100% single cell catch and 60% extraction to external culture well.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.