Abstract

Abstract not available.

Highlights

  • Oral broad-spectrum tetracycline-class antibiotics are prescribed for the treatment of moderate to severe inflammatory acne Poor tolerability and bacterial resistance concerns may limit the use of broad-spectrum tetracycline antibiotics for the treatment of acne

  • In SC1401 and SC1402 (Table 1) IGA success rates were 21.9% and 22.6% versus 10.5% and 15.3%

  • Sarecycline, a narrow-spectrum tetracycline class antibiotic recently FDA-approved for the treatment of moderate to severe acne in ages 9 and older, was safe, well tolerated, and statistically significant at 12 weeks in achieving IGA Success and reduction in inflammatory lesion count

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Summary

Introduction

Oral broad-spectrum tetracycline-class antibiotics are prescribed for the treatment of moderate to severe inflammatory acne Poor tolerability and bacterial resistance concerns may limit the use of broad-spectrum tetracycline antibiotics for the treatment of acne

Design & Methodology
Results
Conclusions
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