Abstract
The locomotor activity of rats injected with apomorphine (1.0 or 5.0 mg/kg) was measured. The increase of locomotion caused by apomorphine was stronger in rats pretreated with BOL or methysergide and in some case with p-chloroamphetamine. LSD did not change the stimulation evoked by apomorphine or decreased it. The results are discussed according to the previously expressed suggestion about the possible inhibitory role of serotonin in apomorphine-induced locomotor stimulation in rats.
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