Abstract
AbstractCholesterol esterification was studied in adult and cord serum by measureing the initial rate of lecithin‐cholesterol acyl transferase (LCAT) activity. Cord serum had about one‐third as much free and esterified cholesterol and about one‐half as much LCAT as adult serum. When the adult LCAT activities are plotted against the individual's serum free cholesterol levels a straight line relationship results (0.101±.005% cholesterol esterified per min). Cord serum LCAT activities (.135±.0407% cholesterol esterified per min) in the main fall above the adult line. Our results show that cord serum can esterify cholesterol at a rate equal to or higher than adult serum when the LCAT activity is related to the amount of serum free cholesterol present.
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