Abstract

Refractive index (RI) sensors based on optical resonance techniques are receiving a high degree of attention because of the need to develop simple, low-cost, high-throughput detection technologies for a number of applications. While the sensing mechanism of most of the reported RI sensors is similar, the construction is quite different from technique to technique. It is desirable to have a uniform mechanism for comparing the various RI sensing techniques, but to date there exists a degree of variation as to how the sensing performance is quantified. Here we set forth a rigorous definition for the detection limit of resonant RI sensors that accounts for all parameters that affect the detection performance. Our work will enable a standard approach for quantifying and comparing the performance of optical resonance-based RI sensors. Additionally, it will lead to design strategies for performance improvement of RI sensors.

Highlights

  • Optical refractive index (RI) sensors are widely researched for a number of applications and are prominent among the commercial landscape of current sensing technologies

  • We have proposed a method for characterizing the performance of RI sensors that utilize optical resonance

  • Instead of relying on the RI sensitivity of the sensor, our method uses a detection limit (DL) that is based on the sensitivity as well as the sensor resolution, where the resolution depends on a number of noise sources

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Summary

Introduction

Optical refractive index (RI) sensors are widely researched for a number of applications and are prominent among the commercial landscape of current sensing technologies. Examples of optical RI sensors include surface plasmon resonance (SPR) [1], 2-D photonic crystal structure [2,3], long-period fiber grating (LPFG) [4,5], and various forms of ring resonators [6,7,8,9,10,11,12,13,14,15]. In these sensors, an optical resonance can be observed; at least a fraction of the corresponding mode is interacting with the sample. The purpose of this correspondence is to put forth a definition for the detection limit for RI sensors for both refractometric and biomolecule sensing applications, and to comment on the factors that determine the detection limit, including RI sensitivity, system resolution, and a number of noise sources

Detection limit
Biomolecule detection limit
Summary and discussion
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