Abstract
Rats ran a runway for brain stimulation reward. From data relating running speed to current intensity at different pulse durations, we determined the strength-duration function. This function describes how much of an increase in current is required to compensate for a given decrease in pulse duration. From this function we calculated total charge (Current × Duration) as a function of duration. This quantity tends toward a constant minimum at short durations (0.1 msec or less). Short pulse durations should minimize the deleterious electrochemical effects of stimulation delivered through chronic electrodes.
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