Abstract
In the γ-globulin fraction obtained from the sera of patients with infectious nonspecific polyarthritis (rheumatoid arthritis) the rheumatoid factor level in the titer was 1.32-1∶512, γ-globulin fractions A, B, and C confirmed by the results of electrophoresis on paper. The agglutinating factor in the titer corresponding to that of the initial serum was detected in the A fraction (obtained by the method of salting out with 19.3% ammonium sulphate in a 4% sodium chloride solution) and in the C fraction (fraction A component, precipitated as the results of the treatment of the former with a 0.4% rivanol solution). Fraction B; a component not precipitated from the serum with a 0.4% rivanol solution, produced no agglutinating activity. The described method of the C fraction isolation may be recommended for obtaining purified rheumatoid factor.
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