Abstract
AbstractMitotic cells grow in volume and divide themselves into two identical cells producing at macroscopic scale a volume expansion in living bodies. Due to inhomogeneous distributions of the growth factors, growth occurs at different rates and directions. Focusing into the direction of growth, some living bodies alter their growing behaviour influenced by mechanical loads. If loads appear during the growth process, cell division is reorientated following the main direction of the elastic deformations. Therefore, new cells will be created in this direction while relaxing the stress state of the body at the same time. In this work, we present a modelling approach for growing bodies which change their growth direction depending on mechanical loads. The model is implemented into a finite element framework to be an useful tool for predicting morphological changes in growing bodies. (© 2016 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)
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