Abstract
Abstract During logarithmic growth Bacillus subtilis synthesizes teichoic acid, but not teichuronic acid. Under conditions of phosphate limitation, teichoic acid synthesis stops, and teichuronic acid synthesis is activated. Suitable radioactive labeling experiments have shown that both of these polymers are attached only to glycopeptide chains synthesized at the same time as these specialized polymers are made. An examination of the teichoic acid glycopeptide complex obtained by lysozyme digestion from cells labeled with d-[3H]glucosamine during a period of phosphate limitation, and with d-[14C]glucosamine after resumption of logarithmic growth, has shown that the glycan chains adjacent to those linked covalently to teichoic acid represent a nearly random selection of new and old chains. This last finding is interpreted to indicate that during cell wall growth there is a random intercalation of new and old glycopeptide chains.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
