Abstract
Summary Four aromatic nitro-compounds have been studied, and it has been found that they are eliminated from 4 species of laboratory animals in the following descending order of speed: p-nitrophenol > 2:4:dinitrophenol > 2:4-dinitro-α-naphthol > 4:6-dinitro-o-cresol. In the 4 species of animals employed the eliminating efficiency in descending order of speed is mouse > rabbit > guinea-pig > rat. A few experiments on West African monkeys reveals that the elimination rates of the 4 substances are of the same order as for the rat. A comparison of the ratios of the LD50 values and of the elimination rates indicates that the LD50 values are much closer numerically than are the elimination rates. The latter exhibit some divergence.
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