Abstract
Coupled extreme environments pose among the highest demands on materials, stressing the limits of temperature, pressure, electric and magnetic fields, atomic displacement rates, and chemical potentials that can be simultaneously sustained. This issue highlights exciting new materials science methods that will enable rapid progress in what has traditionally been the most difficult materials arena. New opportunities in artificial intelligence, multi-physics simulations capabilities, the use of extreme conditions to synthesize novel materials, and our ability to interrogate materials under relevant conditions provide new avenues to understand and design new materials. Graphical abstract
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