Abstract
We develop a combinatorial condition necessary for the existence of a saturated asymmetrical orthogonal array of strength 2. This condition limits the choice of integral solutions to the system of equations in the Bose-Bush approach and can thus strengthen considerably the Bose-Bush approach as applied to a symmetrical part of such an array. As a consequence, several nonexistence results follow for saturated and nearly saturated orthogonal arrays of strength 2. One of these leads to a partial settlement of an issue left open in a paper by Wu, Zhang and Wang. Nonexistence of a class of saturated asymmetrical orthogonal arrays of strength 4 is briefly discussed.
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