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Abstract
AbstractLymph or blood plasma, rich in diamine oxidase (DAO; EC 1.4.3.6.) activity was obtained from donor rabbits, after i.v. injection of heparin. The lymph or, after heparin neutralization, the blood serum was injected into recipient rabbits, and the elimination of the transfused DAO activity was studied. Analogously to earlier findings in man, the elimination rate of transfused DAO activity was several times more rapid than is indicated by the apparent rate of return to normal levels in rabbits, after heparin‐induced increase in blood plasma DAO activity. Furthermore, our findings indicate the possibility of 2 different components of the elimination of transfused postheparin rabbit DAO activity, somewhat contrasting to the findings in man.
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