On the effect of ageing on the distribution of vasoactive intestinal polypeptide and calcitonin gene-related peptide in the rat brain

Jacopo S Andreose,Guido Fumagalli,Francesco Clementi

doi:10.1016/0304-3940(94)90631-9

On the effect of ageing on the distribution of vasoactive intestinal polypeptide and calcitonin gene-related peptide in the rat brain

Jacopo S Andreose, Guido Fumagalli + Show 1 more

https://doi.org/10.1016/0304-3940(94)90631-9

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Journal: Neuroscience Letters	Publication Date: Apr 1, 1994
Citations: 13

Affiliation: University of Milan

#Distribution Of Vasoactive Intestinal Polypeptide #Distribution Of Calcitonin Gene-related Peptide + Show 8 more

Abstract
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Abstract

The distribution of calcitonin gene-related peptide (CGRP) and vasoactive intestinal polypeptide (VIP) was investigated by the use of immunohistochemical techniques in the brain of young and aged rats. CGRP-like immunoreactivity (CGRP-LI) showed a significant decrease only in the amygdala, whereas a substantial age-dependent decrease in VIP-like immunoreactivity (VIP-LI) was observed in the cortex, amygdala, substantia nigra, hippocampus and suprachiasmatic nucleus.

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