On the detection of newer Epo forms in serum and urine using isoelectric focusing

Abstract

American Journal of HematologyVolume 83, Issue 9 p. 754-755 LetterFree Access On the detection of newer Epo forms in serum and urine using isoelectric focusing Joris Delanghe, Corresponding Author Joris Delanghe [email protected] Department of Clinical Chemistry, University Hospital Ghent, BelgiumDepartment of Clinical Chemistry, University Hospital Ghent, BelgiumSearch for more papers by this authorMathieu Bollen, Mathieu Bollen Laboratory of Biosignaling and Therapeutics, Department of Molecular Cell Biology, KU Leuven, Leuven, BelgiumSearch for more papers by this authorMonique Beullens, Monique Beullens Laboratory of Biosignaling and Therapeutics, Department of Molecular Cell Biology, KU Leuven, Leuven, BelgiumSearch for more papers by this author Joris Delanghe, Corresponding Author Joris Delanghe [email protected] Department of Clinical Chemistry, University Hospital Ghent, BelgiumDepartment of Clinical Chemistry, University Hospital Ghent, BelgiumSearch for more papers by this authorMathieu Bollen, Mathieu Bollen Laboratory of Biosignaling and Therapeutics, Department of Molecular Cell Biology, KU Leuven, Leuven, BelgiumSearch for more papers by this authorMonique Beullens, Monique Beullens Laboratory of Biosignaling and Therapeutics, Department of Molecular Cell Biology, KU Leuven, Leuven, BelgiumSearch for more papers by this author First published: 27 May 2008 https://doi.org/10.1002/ajh.21228Citations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Delanghe JR,Bollen M,Beullens M. Testing for recombinant erythropoietin. Am J Hematol 2008; 83: 237– 241. 2 Kwan JT,Pratt RD. The Epoeitin delta study group. Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in predialysis chronic kidney disease patients. Curr Med Res Opin 2007; 23: 307– 311. 3 Peltre G,Thormann W. Evaluation Report of the Urine EPO Test. Paris: Council of the World Anti-Doping Agency (WADA); 2003. 4 Ketterer F. Die gehen da gezielt ran. Die Tageszeitung 2002. 5 Kohler M,Ayotte C,Desharnais P, et al. Discrimination of recombinant and endogenous urinary erythropoietin by calculating relative mobility values from SDS gels. Int J Sports Med 2008; 29: 1– 6. 6 Reicheil C. SDS-PAGE of recombinant and endogeneous erythropoietins: benefits and limitations of the method for application in doping control. Manfred Donike Workshop. 26th Cologne Workshop on Dope Analysis, 2008. Abstract. 7 Lamon S,Robinson N,Sottas PE, et al. Possible origins of undetectable EPO in urine samples. Clin Chim Acta 2007; 385: 61– 66. 8 Franke WW,Heid H. Pitfalls errors and risks of false-positive results in urinary EPO drug tests. Clin Chim Acta 2006; 373: 189– 190. 9 Lasne F,Martin L,Martin JA,de Ceaurriz J. Isoelectric profiles of human erythropoietin are different in serum and urine. Int J Biol Macromol 2007; 41: 354– 357. 10 Mallorqui J,Segura J,de Bolos C, et al. Recombinant erythropoietin found in seized blood bags from sportsmen. Haemotologica 2008; 93: 313– 314. 11 Skibeli V,Nissen-Lie G,Torjesen P. Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin. Blood 2001; 98: 3626– 3634. 12 Kung CK,Goldwasser E. A probable conformational difference between recombinant and urinary erythropoietins. Proteins 1997; 28: 94– 98. 13 Wide L,Bengtsson C,Berglund B,Ekblom B. Detection in blood and urine of recombinant erythropoietin administered to healthy men. Med Sci Sports Exerc 1995; 27: 1569– 1576. Citing Literature Volume83, Issue9September 2008Pages 754-755 ReferencesRelatedInformation