On Research of Pharmacological Activity of “Bioil”, Polyunsaturated Fatty Acids Concentrate

Olena Koshova,Serhii Tanshyn,Nataliia Filimonova,Nataliia Dubinina,Olga Geyderikh,Olena Shakun,Iryna Tishchenko

doi:10.34257/gjmrbvol22is1pg9

Abstract

Polyunsaturated fatty acids (PUFAs) Are involved in the building of cell membranes of the brain, of the visual analyzer, and biological membranes of other organs and tissues. Due to this, they play an important 7 role in 5 the life of humans 8 and animals and are an essential factor of nutrition [1].Fatty acids are the main component of all types of lipids. They vary in length of the carbon chain (short-chain, middle- chain, long-chain), in the presence of double bonds (saturated, monounsaturated, and 12polyunsaturated fatty acids: di-, tri-, tetra-, penta- and hexa-). Based on the location of the first double bond at 3, 6, 7 or 9th carbon atom relatively the methyl end of the molecule, PUFAs are divided into families of ω-3, ω-6, ω-7, and 16 ω-9 respectively [2].

Highlights

National University of Pharmacy Introduction- Polyunsaturated fatty acids (PUFAs) Are involved in the building of cell membranes of the brain, of the visual analyzer, and biological membranes of other organs and tissues
It was established that in rats, which received according to severity of edema, hyperemia, hemorrhage applications of PUFAs concentrate “BIO-IL”, one day 11 availability: after simulation of full-surface stencil wounds there was 0 points - no signes; observed an improvement of condition of wound
According to the received data, the highest reparative activity PUFAs concentrate “BIOIL” showed at 5-8 day of observation, an evidence of this was a significant reduction in wound area in rats by 1,8 and 2,3 times comparing to rats that were no treated

Summary

Introduction

National University of Pharmacy Introduction- Polyunsaturated fatty acids (PUFAs) Are involved in the building of cell membranes of the brain, of the visual analyzer, and biological membranes of other organs and tissues Due to this, they play an important 7 role in 5 the life of humans 8 and animals and are an essential factor of nutrition [1]. The visual analyzer, and biological membranes of Arachidonic acid is the substrate for the synthesis of other organs and tissues Due to this, they play an eicosanoids, leukotrienes and prostaglandins, which are 9 important 7 role in 5 the life of humans 8 and animals biological regulators of the cardiovascular, nervous, and are an essential factor of nutrition [1]

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