Abstract
The contents of six elements (Cl, K, Ca, Fe, Cu, Zn) for medical samples of 30 patients (15 with wilson's disease and 15 with Thalassemia's disease) were determined by proton induced X-ray emission (PIXE) method. In analysis of these samples, abnormal contents of Cu for wilson's disease and of Fe for Thalassemia's disease were observed which shows that for these cases the situation of patient's illness is very serious.
Highlights
Trace elements have an important role in biological systems which in two last decades has grown rapidly
Characteristic X rays produced in sample being irradiated by MeV protons, were for the first time detected by semiconductor Si(Li) X ray detector that had just become available. This analytical method soon became widely accepted in different accelerator laboratories, known under the acronym proton induced X-ray emission (PIXE) — particle induced X ray emission spectroscopy
Performing quantitative PIXE analysis of the thick targets, one should make measurements relative to a standard that has the same matrix as a measured sample
Summary
Trace elements have an important role in biological systems which in two last decades has grown rapidly. Knowledge of the elemental composition of some biological and medical samples is of major interest for both the basic research, and medical treatment and prophylaxis as well [1]. Qualitative and quantitative analyzes of the heavy elements in biological, medical, and environmental specimens are performed using various methods.
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