Abstract

Screening tests for hypotensive substances were conducted on 57 items from 50 plants. Intravenous administration of fractions from Solidago altissima L. (leaves), asparagus, okra, cornhusk, corncob, tassel and bamboo leaves showed falls in blood pressure in SHR and SHRSP, especially the first marked and continuous falls. Furthermore, extracts from Solidago altissima L. and cornhusk were fractionated on columns of silica gel and Sephadex G-50. The crystalline compounds in the cornhusk fraction were identified as adenosine and guanosine. In addition, the hypotensive substance of fraction A1 from Solidago altissima L. may be a glycoprotein with a molecular weight of over 10, 000.

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