Abstract

We analyzed 3344 publications concerned with the health-related effects of resveratrol that occurs in wine and grapes. We discovered that publication activity increased until 2010 and decreased slightly afterwards. The most frequent author keywords were classified into six groups: (1) beverage-related keywords, (2) compound-related keywords, (3) disease-related keywords, (4) effect-related keywords, (5) mechanism-related keywords, and (6) broader keywords. By means of reference publication year spectroscopy, we analyzed and discussed the most frequently cited references (i.e., key papers) within the publication set. A rather large portion of the key papers exhibit a deliberative or positive attitude and report on the health effects of resveratrol, although limited data in humans preclude drawing unambiguous conclusions on its health-related benefits. From our analysis, we could not identify specific publications that provide a distinct change of direction of the ongoing scientific discourse. Moderate red wine consumption seems to bear the potential of being health promoting, whereas excessive alcohol consumption can induce liver cirrhosis and cancer.

Highlights

  • Moderate red wine consumption seems to bear the potential of being health promoting, whereas excessive alcohol consumption can induce liver cirrhosis and cancer

  • This study aims to reveal the key papers of the scientific discourse concerning the relationship between resveratrol as a specific polyphenol in wine and health effects, based on an analysis of the most-cited papers within a carefully selected publication set

  • A comparatively large portion of the key papers revealed by the Reference Publication Year Spectroscopy (RPYS) spectrogram and the N_TOP10 indicator takes a deliberative or positive attitude and reports about health effects of resveratrol

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Summary

Objectives

This study aims to reveal the key papers of the scientific discourse concerning the relationship between resveratrol as a specific polyphenol in wine and health effects, based on an analysis of the most-cited papers within a carefully selected publication set. This study aims to reveal those papers that have been cited comparatively often within the scientific discourse on health effects of the specific polyphenol resveratrol in wine

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