On Golgi’s Internal Apparatus in spontaneously absorbing Tumour Cells.1

Abstract

ABSTRACT In continuation of previous work the behaviour of Golgi’s apparatus during spontaneous absorption of transplantable tumours of the mouse is described. In some of them the apparatus soon becomes transformed into a granular almost structureless material ; in others this terminal phase is reached through stages which are probably determined by the characteristic structure exhibited by the apparatus in the healthy cells of the corresponding tumours. The modifications of the apparatus during such stages have a striking resemblance with the changes observed in different tissues under various physiological conditions. The connective-tissue cells, which invade the tumours as they are absorbed, are provided with a small, irregular, and sometimes reticular apparatus which is identical with that described by other authors in similar elements though in different pathological processes. In some of these elements the apparatus undergoes changes not altogether different from those observed in absorbing tumour cells. In general, the fragmentation of the apparatus begins when other cell constituents are still apparently unaltered, but its fragments seem to possess a great power of resistance to degenerative conditions.