Abstract
To investigate the differential age-duration effects of isolation in promoting attacks and fighting in male laboratory mice ( Mus musculus), a factorial study of five different isolation intervals (0, 4 0, 4 1, 4 2, 4 3 days) initiated at five different ages (21, 28, 35, 56, 84 days since birth) was completed. Five hundred ICR mice (250 experimental isolates; 250 control partners) were studed in a procedure that yielded detailed information on the interactional processes that led up to attacks and fighting. In addition, measures of non-social reactivity and weight were taken for all animals. The results provide strong support for the time of isolation, the duration of isolation, and the developmental status of the partner. Beyond the notion of a sensitive period, the results indicate that the effects of isolation are superimposed upon species-typical developmental changes in both the subject and the partner.
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