Abstract
Sample introduction on to capillary columns includes evaporation of the sample as an important step. Except for volatile substances, this evaporation step entails deleterious effects and is the primary cause of the limited precision and accuray of quantitative analyses performed with capillary columns. A second factor that limits the potential of capillary columns is the injection septum. A solution to the problems seems to be on-column injection by means of an injector functioning without a septum. There are important arguments in favour of maintaining the classical syringe for injection, and such an injector is described and some examples of applications are given.
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