Abstract
Female albino rats were daily X-ray irradiated during the whole period of pregnancy in a dose of 1 r. After establishment of the coitus date by the presence of spermatozoa in the vaginal smear they were irradiated 20 days in succession, the total dose being 20 r. A study was made of the higher nervous activity of adult rats subjected to such irradiation during the whole period of embryonic development. There was some reduction in the strength of the main nervous processes in the antenatally irradiated animals in comparison with controls. The following was noted: a slower adaptation to the experimental surrounding environment, retarded conditioned reflex elaboration, prolongation of the latent periods and diminution of the positive conditioned reflex values. In these rats a more frequent loss of conditioned reflexes was noted. The functional tests with caffeine and starvation also point to the reduction of the stimulation and inhibition processes. The brain of the irradiated rats is of low weight and its cortex in the frontal portions is thin.
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